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Gene Expression Literature Summary
Assay
Age
In situ RNA (section)
14.5 DPC

26 matching records from 26 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Otx2  orthodenticle homeobox 2   (Synonyms: E130306E05Rik)
Results  Reference
1*J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1J:159104 Cai Z, Feng GS, Zhang X, Temporal requirement of the protein TyrosinePhosphatase Shp2 in establishing the neuronal fatein early retinal development. J Neurosci. 2010 Mar 17;30(11):4110-9
1J:165076 Cammas L, Trensz F, Jellali A, Ghyselinck NB, Roux MJ, Dolle P, Retinoic acid receptor (RAR)-alpha is not critically required for mediating retinoic acid effects in the developing mouse retina. Invest Ophthalmol Vis Sci. 2010 Jun;51(6):3281-90
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:309996 Dumas S, Wallen-Mackenzie A, Developmental Co-expression of Vglut2 and Nurr1 in a Mes-Di-Encephalic Continuum Preceeds Dopamine and Glutamate Neuron Specification. Front Cell Dev Biol. 2019;7:307
1J:97456 Fossat N, Courtois V, Chatelain G, Brun G, Lamonerie T, Alternative usage of Otx2 promoters during mouse development. Dev Dyn. 2005 May;233(1):154-60
1J:229533 Kouwenhoven WM, Veenvliet JV, van Hooft JA, van der Heide LP, Smidt MP, Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function. Biol Open. 2016;5(3):279-88
1J:157828 Lancioni A, Pizzo M, Fontanella B, Ferrentino R, Napolitano LM, De Leonibus E, Meroni G, Lack of Mid1, the mouse ortholog of the Opitz syndrome gene, causes abnormal development of the anterior cerebellar vermis. J Neurosci. 2010 Feb 24;30(8):2880-7
1J:79431 Li JY, Lao Z, Joyner AL, Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron. 2002 Sep 26;36(1):31-43
1J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027
1*J:270210 Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ, Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134
1J:181993 Luo H, Jin K, Xie Z, Qiu F, Li S, Zou M, Cai L, Hozumi K, Shima DT, Xiang M, Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):E553-62
1*J:171624 Machold R, Klein C, Fishell G, Genes expressed in Atoh1 neuronal lineages arising from the r1/isthmus rhombic lip. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):349-59
1J:309395 Martinez-Ferre A, Lloret-Quesada C, Prakash N, Wurst W, Rubenstein JL, Martinez S, Fgf15 regulates thalamic development by controlling the expression of proneural genes. Brain Struct Funct. 2016 Jul;221(6):3095-109
1J:310179 Moreno-Bravo JA, Perez-Balaguer A, Martinez-Lopez JE, Aroca P, Puelles L, Martinez S, Puelles E, Role of Shh in the development of molecularly characterized tegmental nuclei in mouse rhombomere 1. Brain Struct Funct. 2014 May;219(3):777-92
1*J:175980 Mortensen AH, MacDonald JW, Ghosh D, Camper SA, Candidate genes for panhypopituitarism identified by gene expression profiling. Physiol Genomics. 2011 Oct 6;43(19):1105-16
1J:218295 Mortensen AH, Schade V, Lamonerie T, Camper SA, Deletion of OTX2 in neural ectoderm delays anterior pituitary development. Hum Mol Genet. 2015 Feb 15;24(4):939-53
1J:98698 Muzio L, Mallamaci A, Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. J Neurosci. 2005 Apr 27;25(17):4435-41
1J:63216 Nguyen M, Arnheiter H, Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF. Development. 2000 Aug;127(16):3581-91
1J:160263 Nielsen CM, Dymecki SM, Sonic hedgehog is required for vascular outgrowth in the hindbrain choroid plexus. Dev Biol. 2010 Apr 15;340(2):430-7
1J:133489 Qiu F, Jiang H, Xiang M, A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors. J Neurosci. 2008 Mar 26;28(13):3392-403
1*J:93571 Rowan S, Chen CM, Young TL, Fisher DE, Cepko CL, Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development. 2004 Oct;131(20):5139-52
1J:155409 Santagata S, Maire CL, Idbaih A, Geffers L, Correll M, Holton K, Quackenbush J, Ligon KL, CRX is a diagnostic marker of retinal and pineal lineage tumors. PLoS One. 2009;4(11):e7932
1*J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
1*J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory